Our patients are on the 2nd-4th day of the menstrual cycle. After the initial ultrasonography is performed and the blood hormone levels are checked, injections to stimulate the ovaries are started. You should have the injections done at the same time every day. Since the daily dose adjustments are determined in the afternoon, it is preferred that you get the injections between 18:00 and 21:00 every day. A medicine report describing your medicine doses will be given to you by our nurses.
Gonadotropin needles (Gonal-f, Merional, Fostimon etc.): These needles are used from the beginning of menstruation and to enlarge and reproduce eggs.
GnRH analogs (Lucrin, Decapeptyl etc.): These needles are used to prevent the hatching of the grown eggs before the planned time. Some
In patients, these needles are used in the last maturation period of the eggs.
Gonadotropin injections (Gonal-f, Merional, Fostimon etc.):
These needles are used from the beginning of menstruation and to grow and reproduce eggs.
GnRH analogs (Lucrin, Decapeptyl etc.):
These needles are used so that the grown eggs do not hatch before the scheduled time. In some patients, these needles are used in the last maturation period of the eggs.
GnRH Antagonists (Cetrotide, Orgalutran):
These needles are different groups of needles used to prevent premature cracking of your eggs.
Cracking Needle-HCG (Pregnyl, Ovitrelle):
Mature eggs are usually obtained from follicles over 15 mm in diameter. Preferably, HCG is administered when 3 or more follicles reach over 17 mm and/or blood E2 level is more than 500 pg/ml. The purpose of applying the cracker needle is not to crack the eggs, but to ensure the final maturation of the eggs. Before the eggs hatch, they must be collected. Egg retrieval is usually done 36 hours after the HCG hour. HCG administration time is extremely important. It is imperative that you comply exactly with the time given to you.
Pregnyl; It consists of powder and solvent water containing 5000 units. There is 1 powder, 1 water in a box. Unless otherwise specified, 2 powders and 1 water, ie 10000 units, are made from the hips. Ovitrelle, 250 mg. It is available in the injector as ready-to-use and is performed subcutaneously.
Femara:
It is used to use less injection doses and to sensitize the ovaries in cases where very weak ovarian response is expected.
Progesterone (Crinone, Proluton):
Progesterone is released from the ovaries and makes the uterine wall suitable for embryo attachment. Due to the drugs we use, progesterone hormone support must be provided in IVF applications. Progesterone use; slight weight gain, mood changes, pain at the injection site if an injection is given, and breast swelling. If pregnancy does not occur, menstruation may be delayed a little because progesterone is used.
Changing the Treatment Plan:
In approximately 10% of cases, the treatment is canceled without HCG administration. The most important reasons for cancellation may be insufficient follicle development, significant diameter mismatch between follicles. Sometimes extremely high E2 values such as 4500-5500 pg/ml can be reached during treatment. In this case, treatment may be canceled for ovarian hyperstimulation.